Abstract
Carbon nanotubes (CNTs), a carbon allotrope with various physicochemical properties, have gained worldwide interest since last two decades. CNTs are made up of cylindrical shaped graphene foils with nanometric dimension and several micrometres in length. The application of CNTs in the field of pharmacy and medicine is based on their large surface area capable to adsorb or conjugate various classes of drugs, genes, vaccines, and antibodies. This review focuses on the applicability of CNTs as targeted drug delivery vehicle considering the biopharmaceutics and toxicokinetics including advantages, obstacles, and perspectives of various CNTs.
Keywords: Biodistribution, Carbon nanotubes, CNS targeting, Drug targeting, Gene therapy, Lymphatic targeting, Macrophage targeting, PEGylated CNTs, Pharmacokinetics, Toxicity, Tumor targeting, Vaccine delivery.
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