Abstract
Transdermal drug delivery is a well-accepted route of administration for therapeutical drugs. Skin is the largest area human body organ, however, the substantial barrier property of the skin stratum corneum limits practical value of transdermal route of drug administration. It has been proved that microneedle array devices can overcome the barrier characteristics of the stratum corneum and enhance the delivery of therapeutic medicines through skin. This chapter focuses on looking at the microneedle-mediated transdermal drug delivery for therapeutical applications. The definition of microneedles, enhancement mechanisms and devices in research or in the market are also depicted.
Keywords: Definition, Devices in research or in the market, Mechanisims of action, Microneedle, Therapeutical applications.
About this chapter
Cite this chapter as:
Yunhua Gao, Yuqin Qiu, Suohui Zhang ;Microneedles, Current Technologies To Increase The Transdermal Delivery Of Drugs Physical Penetration Enhancers: Therapeutic Applications and Devices (2016) 2: 210. https://doi.org/10.2174/9781681083636116020010
DOI https://doi.org/10.2174/9781681083636116020010 |
Print ISSN 2468-7375 |
Publisher Name Bentham Science Publisher |
Online ISSN 2468-7383 |